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Microbiology

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Gram Negative Bacilli

Question
21 out of 81
 

Regarding E.coli
Assertion: there is no
successful vaccine against E. coli infection

Reason: serotypic diversity of both surface antigens and toxins



A Both Assertion and Reason are true, and Reason is the correct explanation for Assertion

B Both Assertion and Reason are true but Reason is not the correct explanation for Assertion

C Assertion is true but Reason is false

D Reason is true but Assertion is false

Ans. A Both Assertion and Reason are true, and Reason is the correct explanation for Assertion

a.A fully successful vaccine against E. coli infection has not yet emerged, because of the serotypic diversity of both surface antigens and toxins.

b. However, trials have been conducted with toxoids based on the enterotoxins, purified fimbriae, whole killed organisms and live attenuated strains, all of which give some protection.

c.The combined killed cholera/B toxin subunit vaccine gives significant protection against ETEC because of cross-reaction between the two toxins

Gram Negative Bacilli Flashcard List

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