Metabolic Bone Diseases
Regarding OSTEOPETROSIS all the following statements are true except? (AIIMS May 2011)
|B||Delayed fracture healing|
|C||Cranial nerve compression|
|D||Osteomyelitis of mandible|
Delayed fracture healing
Bone healing takes normal time.
a. As bone and cartilage fail to undergo modeling, paralysis of one or more cranial nerves may occur due to narrowing of the cranial foramina.
b. Failure of skeletal modeling also results in inadequate marrow space, leading to extramedullary hematopoiesis with hypersplenism and pancytopenia.
c. Hypocalcemia due to lack of osteoclastic bone resorption may occur in infants and young children.
d. Factures may be accompanied by loss of vision, deafness, psychomotor delay, mandibular osteomyelitis.
a. Typically, there are generalized symmetric increases in bone mass with thickening of both cortical and trabecular bone.
b. The cranium is usually thickened, particularly at the base of the skull, and the paranasal and mastoid sinuses are underpneumatized.