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Orthopaedic

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Metabolic Bone Diseases

Question
39 out of 42
 

Regarding osteomalacia



A Is due to vitamin A deficiency

B Can cause a distal myopathy

C May present with pseudo-fractures

D Serum calcium is increased

E A bone biopsy would show an increase in mineralised osteoid

Ans. C

May present with pseudo-fractures

a. Osteomalacia is due to vitamin D deficiency. It can result from malabsorption, renal disease (familial hypophosphataemic rickets), chronic renal failure and anticonvulsant therapy.

b. It often presents with bone pain and a proximal myopathy. Serum calcium is low.

c. A bone biopsy would show an increase in the amount of unmineralised osteoid.

Metabolic Bone Diseases Flashcard List

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