Metabolic Bone Diseases
|A||Is due to vitamin A deficiency|
|B||Can cause a distal myopathy|
|C||May present with pseudo-fractures|
|D||Serum calcium is increased|
|E||A bone biopsy would show an increase in mineralised osteoid|
May present with pseudo-fractures
a. Osteomalacia is due to vitamin D deficiency. It can result from malabsorption, renal disease (familial hypophosphataemic rickets), chronic renal failure and anticonvulsant therapy.
b. It often presents with bone pain and a proximal myopathy. Serum calcium is low.
c. A bone biopsy would show an increase in the amount of unmineralised osteoid.