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Pharmacology

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Question
7 out of 45
 

Relative to filgrastim (G-CSF), sargramostim (GM-CSF) (AIIMS Nov 2009)



A Has greater oral bioavailability

B Is more likely to cause thrombocytopenia

C Is more likely to elicit an allergic reaction Q

D Is more likely to prevent fevers in neutropenic patients

E Stimulates production of a wider variety of hematopoietic stem cells

Ans. E Stimulates production of a wider variety of hematopoietic stem cells

GM-CSF has wider biologic activity than G-CSF; it stimulates early myeloid stem cells in addition to cells destined to become neutrophils.

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