Relative to filgrastim (G-CSF), sargramostim (GM-CSF) (AIIMS Nov 2009)
|A||Has greater oral bioavailability|
|B||Is more likely to cause thrombocytopenia|
|C||Is more likely to elicit an allergic reaction Q|
|D||Is more likely to prevent fevers in neutropenic patients|
|E||Stimulates production of a wider variety of hematopoietic stem cells|
GM-CSF has wider biologic activity than G-CSF; it stimulates early myeloid stem cells in addition to cells destined to become neutrophils.