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Physiology

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Kidney

Question
5 out of 8
 

Relaxation of mesangial cells of kidney is brought about by (LQ)



A Endothelin

B PGF2

C Option A,B is right

D Vasopressin

Ans. A Camp

Mesangial cells: -

a. Contraction of the mesangial cells decrease Kf

b. Kf = “glomerular ultrafiltration coefficient” is the product of the glomerular capillary wall hydraulic conductivity (i.e. its permeability) and the effective filtration surface area

c. Kf controls the GFR: -GFR=Kf [(PGC –PT) – (GC T)]

d. Agents causing contraction or relaxation of mesangial cells: -

Contraction

Relaxation

Endothelins

Angiotensin II

Vasopressin

Nor-epinephrine

Platelet -activation factor

Platelet-derived growth factor

Thromboxane A2

PGF2

LT-C4 and D4

Histamine

ANP

Dopamine

PGE2

cAMP Q