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Medicine

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Rheumatology

Question
20 out of 50
 

Renal artery stenosis may occur in all of the following, except: (AIPG 06)



A Atherosclerosis

B Fibromuscular dysplasia

C Takayasu's arteritis

D Polyarteritisnodosa

Ans. D Polyarteritisnodosa

A. Polyarteritisnodosa (classic polyarteritisnodosa) (Ref: H-18th edition, Pg-2794)

i. Necrotizing inflammation of medium-sized or small arteries without glomerulonephritis or vasculitis in arterioles, capillaries, or venules

ii. Granuloma, &Eosinophilic are not the features of PAN (They are features of Churg Strauss disease).

iii. Aneurysmal dilatations along the involved arteries are characterstic of PAN.

iv. RAS is not a feature. (AIPG 2006)

v. Lungs and Spleen vessels are not involved.

vi. Numbness of multiple limbs indicates peripheral neuropathy / mononeuritis multiplex.

vii. Digital gangrene forms part of the typical skin findings in PAN.

viii. Hypertension is a common manifestation of renal involvement in PAN.

ix. Renal failure can occur.

x. Diseases associated in PAN (a) Hepatitis B (b) Hairy cell leukemia (H-18thPg- 2794)

Clinical manifestations related to organ system involvement in classic polyarteritisnodosa (H-18thPg- 2794, table 326.6)

System

%

Features

Renal

60

Hypertension, Renal failure

Musculoskeletal

64

Arthritis, arthralgia, myalgia

PNS

51

Peripheral neuropathy, mononeuritis multiplex

GIT

44

Abdominal pain, nausea and vomiting, bleeding, bowel infarction and perforation, cholecystitis, hepatic infarction, pancreatic infarction.

Skin

43

Rash, purpura, nodules, cutaneous infarcts, livedoreticularis, Raynaud phenomenon

Cardiac

36

Congestive heart failure, myocardial infarction, pericarditis

Genitourinary

25

Testicular, ovarian, or epididymal pain

CNS

23

Cerebral vascular accident, altered mental status, seizure.

Rheumatology Flashcard List

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