Loading....
Coupon Accepted Successfully!

 

Occupational Lung Diseases

  1. Silicosis
     
    Silicosis is caused by inhalation of silica particles.
     
    Clinical features: Progressive dyspnoea, incidence of TB Q,
     
    CXR shows diffuse miliary or nodular pattern in upper and mid-zones and egg-shell calcification Q of hilar nodes.
     
    CT scan: There is a characteristic HRCT pattern known as "crazy paving" (Ref. Hari. 18th ed. Pg - 2124)

Spirometry: restrictive Q defect

 

Important Points:

  1. Silicosis has predilection for upper lobes
  2. Silicosis is associated with calcific Hilar Adenopathy
  3. Silicosis is associated with Tuberculosis (LQ 2012) 
  1. COAL WORKER’S PNEUMOCONIOSIS (CWP)
    1. Coal worker’s pneumoconiosis (CWP) results from inhalation of coal dust particles (1-3 micro m in diameter) over 15-20yr. These are ingested by macrophages which die, releasing their enzymes and cause fibrosis Q.
    2. CXR: many round opacities (l-10mm), especially upper zone Q.
    3. Progressive massive fibrosis (PMF) is due to progression of CWP, which can cause progressive dyspnoea. fibrosis, and eventually, cor pulmonale Q.
    4. CXR: upper zone fibrotic masses
    5. Caplan's syndrome is the association between rheumatoid arthritis, pneumoconiosis Q, and pulmonary rheumatoid Q nodules. 
  2. ASBESTOSIS
    1. Asbestosis is caused by inhalation of asbestos fibres. Ferruginous bodies Q are present.
    2. White asbestos is the least fibrogenic blue asbestos is the most fibrogenic.
    3. Clinical features: Similar to other fibrotic lung diseases with progressive dyspnoea, clubbing Q, and fine end-inspiratory crackles.
    4. Also causes pleural plaque Q risk of bronchial adenocarcinoma Q and mesothelioma Q.
    5. Asymptomatic, pleural plaque Q is the commonest findings.
    6. Malignant mesothelioma is a tumour of mesothelial cells which usually occur in the pleura and rarely in the peritoneum or other organs. It is associated with occupational exposure to asbestos Q.

Asbestos Related Lung Disease

Pulmonary

Pleural

Non malignant

Malignant

Non malignant

Malignant

Diffuse interstitial

Fibrosis (Asbestosis)

Bronchogenic Carcinoma is the most common cancer associated with asbestos exposure.

Pleural plaques is the

M/C manifestation

Mesothelioma

 

Clinical features include chest pain, dyspnoea weight loss, finger clubbing Q, recurrent pleural effusions Q.

 

If the tumour has metastasized there may lymphadenopathy, hepatomegaly, bone pain/tenderness, abdominal pain/obstruction (peritoneal malignant mesothelioma).

  1. Idiopathic Pulmonary Hemosiderosis (IPH)

IPH is a disorder of unknown etiology characterized by recurrent episodes of Diffuse Alveolar Hemorrhage (DAH)

 

It has been classically characterized by the triad of

  1. Iron deficiency Anemia
  2. Hemoptysis
  3. Alveolar infiltrates on chest radiographs




Test Your Skills Now!
Take a Quiz now
Reviewer Name