Retrolental fibroplasia is because of: (AIPG 2010)
4. Retrolental fibroplasia occurs in premature infants treated with oxygen at concentrations above ambient air levels.
5. The increased arterial oxygen tensions that result may lead to severe arterial vasoconstriction with subsequent hypoxic damage to the immature retina.
6. The exact level or duration of elevated arterial pO2 that results in injury is not known, but arterial oxygen tension should be kept between 50-80 mmHg. Immaturity and periods of relative retinal HYPEROXIA are considered to be major factors in the development of this disorder.