General Virology and DNA Viruses
Reverse transcriptase is an enzyme found in retroviruses and hepadnaviruses. Which one of the following is a function of the enzyme reverse transcriptase?
|B||DNA-dependent RNA polymerase activity|
|C||RNA-dependent DNA polymerase activity|
|D||RNA-dependent RNA polymerase activity|
a. The replication of a retroviral genome is dependent on the reverse transcriptase enzyme, which performs a variety of functions.
b. It builds a complementary strand of DNA for the viral RNA template; it builds a second DNA strand complementary to the previous DNA;
c. it degrades the original RNA, leaving a DNA-DNA duplex; and, finally, it is responsible for integrating the new viral DNA hybrid into the host genome.