6 out of 42
Rh factor is (AIPG 2008)
Ans. B Mucopolysaccharide
- Aside from the antigens of the ABO system, those of the Rh system are of the greatest clinical importance.
- The "Rh factor," named for the rhesus monkey because it was first studied using the blood of this animal, is a system composed primarily of the C, D, and E antigens.
- The terms Rhesus factor and Rh factor are equivalent and refer to the Rh D antigen.
- Unlike the ABO antigens, the system has not been detected in tissues other than red cells. D is by far the most antigenic component, and the term "Rh-positive" as it is generally used means that the individual has agglutinogen D.
- The "Rh-negative" individual has no D antigen and forms the anti-D agglutinin when injected with D-positive cells.
- The Rh typing serum used in routine blood typing is anti-D serum.
- Eighty-five percent of Caucasians are D-positive and 15% are D-negative; over 99% of Asians are D-positive.
- Most of the blood group antigens are proteins or mucopolysaccharides, so most likely Rh factor is a Mucopolysaccharide.