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Physiology

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Blood

Question
6 out of 42
 

Rh factor is (AIPG 2008)



A IgM antibody
B Mucopolysaccharide

C IgG Antibody
D Fatty acid

Ans. B Mucopolysaccharide
  1. Aside from the antigens of the ABO system, those of the Rh system are of the greatest clinical importance.
  2. The "Rh factor," named for the rhesus monkey because it was first studied using the blood of this animal, is a system composed primarily of the C, D, and E antigens.
  3. The terms Rhesus factor and Rh factor are equivalent and refer to the Rh D antigen.
  4. Unlike the ABO antigens, the system has not been detected in tissues other than red cells. D is by far the most antigenic component, and the term "Rh-positive" as it is generally used means that the individual has agglutinogen D.
  5. The "Rh-negative" individual has no D antigen and forms the anti-D agglutinin when injected with D-positive cells.
  6. The Rh typing serum used in routine blood typing is anti-D serum.
  7. Eighty-five percent of Caucasians are D-positive and 15% are D-negative; over 99% of Asians are D-positive.
  8. Most of the blood group antigens are proteins or mucopolysaccharides, so most likely Rh factor is a Mucopolysaccharide.

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