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Pathology

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Inflammation

Question
3 out of 13
 

Role of P-selectin in inflammation – (AIIMS Nov 2013)



A Rolling

B Adhesion

C Homing

D Transmigration

Ans. C Homing

Endothelial – Leukocyte Adhesion Molecules

Endothelial molecule

Leucocyte Molecule

Major Role

P-selectin

Sialyl-Lewis X-modified proteins

Rolling (neutrophils, monocytes, L lymphocytes)

E-selectin

Sialyl-Lewis X-modified proteins

Rolling and adhesion (neutrophils, monocytes, T lymphocytes)

GlyCam-1, CD34

L-selectin

Rolling (neutrophils, monocytes)

ICAM-1 (Immunoglobulin family)

CD11/CD18 102 integrin (LFA-1, Mac-1)

Adhesion, anrest, transmigration (neutrophils, monocytes, lymphocytes)

VCAM-1 (Immunoglobulin family)

VLA-4 β-1 integrin

Adhesion (eosinophils, monocytes, lymphocytes)

Inflammation Flashcard List

13 flashcards
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