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Physiology

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Endocrinology

Question
8 out of 50
 

Sertoli cells in the testis have receptors for? (AIIMS NOV 2007)



A FSH
B LH

C Inhibin
D All of the above

Ans. A FSH

Explanation: FSH helps in maintaining the spermatogenic epithelium by stimulation of Sertoli cells in the male. FSH acts on the sertoli cells to facilitate the late stages of spermatid maturation. In addition, it promotes the production of ABP

  1. Sertoli cell (a kind of sustentacular cell) is a 'nurse' cell of the testes which is part of a seminiferous tubule.
  2. It is activated by follicle-stimulating hormone, and has FSH-receptor on its membranes.
  3. FSH binds to Sertloi cells stimulate testicular fluid production and synthesis of intracellular androgen receptor proteins. Sertoli cells secrete anti- mullerian hormone and activins also.
  4. LH binds to receptors on interstitial cells of Leydig and stimulate testosterone production, which in turn binds to Sertoli cells to promote spermatogenesis.
  5. Inhibin is a hormone that inhibits FSH production. It is secreted from the Sertoli cells, located in the seminiferous tubule inside the testes.

Endocrinology Flashcard List

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