Gram Negative Bacilli
Several children are hospitalized with bloody diarrhea and severe hematological abnormalities. A 4-year-old girl dies of kidney failure shortly after admittance. An epidemiological investigation establishes that all of the patients developed symptoms following consumption of hamburgers from the same fast-food restaurant chain. Which of the following organisms is most likely to be responsible for the outbreak? (AIPG 2010)
|B||Non-O1 serogroup of Vibrio cholerae|
|C||O157:H7 serotype of E. coli|
O157:H7 serotype of E. coli.
a. Escherichia coli 0157:H7 strains are classically associated with outbreaks of diarrhea after ingestion of undercooked hamburger at fast-food restaurants.
b. Many cases of hemorrhagic colitis and its associated complications can be prevented by thoroughly cooking ground beef.
c. The other organisms listed can cause gastrointestinal disturbances; however, E. coli is the classic disturbing pathogen in this case.
d. Shigella dysenteriae produces a heat-labile enterotoxin that affects the gut and central nervous system and is a human disease that is transmitted via a fecal-oral route.
e. Salmonella and Campylobacter are associated with poultry and eggs primarily, whereas Vibrio is associated mainly with seafood.