Splenectomy is most useful in: (AIIMS May 2009)
|D||Sickle cell anemia|
Treatment of choice is do Splenectomy after 14–15 years of age
1. Splenectomy: This is indicated
a. When anemia causes health impairment
c. Aplastic crises (Percolated by Parvovirus infection)
d. Evidence of cholecystitis and cholelithiasis is present
Pneumococcal vaccine should be given 1–2 months prior to splenectomy.
2. Daily penicillin V, 250 mg 12 hourly is prescribed for at least 5 years following splenectomy.
3. Blood transfusion in severe haemolytic crises.
4. Folic acid 5 mg per day orally is prescribed to support the increased erythropoiesis
Extra Edge: Causes of spherocytosis in peripheral smear
1. Hereditary spherocytosis
2. Immunohemolytic anemias (Autoimmune hemolytic anemias)
3. In association with hemolysis induced by splenomegaly in patients with cirrhosis
4. Clostridial infections