Statement not true about "Niemann Pick disease' is:
|A||Deficiency of enzyme sphingomyelinase|
|B||Progressive mental retardation|
a. Premature cataract is not a feature of Niemann Pick disease.
b. In Niemann Pick disease clinical manifestations become evident by 6 months of age. The clinical features includes protuberant abdomen due to hepatosplenomegaly, mental retardation, failure to thrive, vomiting, fever and generalized lymphadenopathy. The condition is fetal in early life.
Sphingolipidoses Enzyme deficiency
Fabry's disease -Galactosidase
Gaucher's disease β-Glucosidase
Niemann-Pick disease Sphingomyelinase
Farber's disease Ceramidase