Stilbestrol administered during pregnancy can produce which of the following effects in the offspring: (DNB Dec 2011)
|A||Virilization of lower limbs|
|B||Vaginal adenocarcinoma in teenage|
|C||Virilization of head and neck|
|D||None of the above|
Vaginal adenocarcinoma in teenage
a. Given to pregnant women, especially during first trimester, stilboestrol increased incidence of vaginal and cervical carcinoma in the female offspring in childhood or early adulthood has been noted.
b. Genital abnormalities are possible in male offspring.