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Physiology

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Central Nervous System

Question
18 out of 18
 

Stomach secretes which of the following which controls appetite (AIIMS nov 2010)



A CCK
B Ghrelin

C Orexin
D insulin like growth factor

Ans. B Ghrelin

a. Ghrelin is a hormone produced mainly by P/D1 cells lining the fundus of the human stomach and epsilon cells of the pancreas that stimulates hunger.

b. Ghrelin levels increase before meals and decrease after meals.

c. It is considered the counterpart of the hormone leptin, produced by adipose tissue, which induces satiation when present at higher levels.

d. In some bariatric procedures, the level of ghrelin is reduced in patients, thus causing satiation before it would normally occur.

e. Ghrelin is also produced in the hypothalamic arcuate nucleus, where it stimulates the secretion of growth hormone from the anterior pituitary gland.

f. The ghrelin receptor is a G protein-coupled receptor. Receptors for ghrelin are expressed by neurons in the arcuate nucleus and the lateral hypothalamus.

g. brown fat through UCP 1.

Mechanisms activated by cold in body

a. Shivering b. Hunger

c. Increased voluntary activity d. Increased secretion of norepinephrine and epinephrine

e. Decreased heat loss f. Cutaneous vasoconstriction

g. Curling up h. Horripilation

Central Nervous System Flashcard List

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