TRUE about the Side-effects of Tetracycline include all of the following EXCEPT
|A||Can cause Pseudotumor cerebri|
|B||NOT teratogenic if used during pregnancy|
|C||Discoloration of teeth may occur|
|D||Superinfection can occur|
Adverse effects of tetracycline
a. Irritative effects: Tetracyclines can cause epigastric pain, nausea, vomiting and diarrhea by their irritant property.
b. Dose related toxicity
i. Liver damage: Fatty infiltration of liver and jaundice occurs occasionally.
ii. Kidney damage: A reversible Fanconi syndrome
iv. Teeth and bones: Given during late pregnancy or childhood, tetracyclines can cause temporary suppression of bone growth. The ultimate effect on stature is mostly insignificant, but deformities
v. and reduction in height are a possibility with prolonged use.
vi. Anti anabolic effect
vii. Increased intracranial pressure
viii. Diabetes insipidus
ix. Vestibular toxicity