Coupon Accepted Successfully!


Open Flashcards

Liver & GIT

4 out of 4

Tegaserod is (PNQ)

A 5-HT4 agonist
B 5-HT4 antagonist

C 5-HT1 antagonist
D 5-HT1 agonist

Ans. A 5-HT4 agonist

Recent Advances: (H-18thPg- 2500)

a. Bifidobacteriuminfantis showed significant improvement in the composite score for abdominal pain, bloating/distention, and/or bowel movement.

b. Tegaserod: It is used for the short-term treatment of women with IBS whose primary bowel symptom is constipation. Tegaserod a selective and partial agonist at the 5-HT4.exhibitprokinetic activity by stimulating peristalsis

c. Lubiprostoneis a bicyclic fatty acid that stimulates chloride channels in the apical membrane of intestinal epithelial cells.