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4 out of 5

The Henderson-Hasselbalch equation is used for measuring: (LQ)

A The sodium potassium balance

B The acid base balance

C The kinetics of enzymatic reaction

D Anion gap

Ans. B The acid base balance

I. Arterial pH is maintained between 7.35 and 7.45 by extracellular and intracellular chemical buffering together with respiratory and renal regulatory mechanisms.

II. The control of PaCO2 the CNS and respiratory systems and the control of the plasma HCO3- by the kidneys stabilize the arterial pH by excretion or retention of acid or alkali The metabolic and respiratory components that regulate systemic pH are described by the Henderson-Hasselbalch equation: Q

[ HCO3-]

pH = 6.1 + log --------------------

PaCO2 x 0.0301