Loading....
Coupon Accepted Successfully!

Biochemistry

Open Flashcards

Vitamins, Harmones and Hemoglobin

Question
3 out of 82
 

The activity of the following enzyme is affected by biotin deficiency :



A Transketolse

B Dehydrogenase

C Oxidase

D Carboxylase

Ans. D carboxylase

Vitamin

Enzymes in which it acts as coenzyme

Deficiency disease

1. Vit. B (Thiamine)

Pyruvate dehydrogenase complex

Oxidative decarboxylation ofα-

keto-acid

Transketolase reaction

Tryptophan pyrrolase

Beri-Beri disease

Wernicke encephalopathy

2. Vit. B2 (Riboflavin) (heat stable but light sensitive)

FMN and FAD are 2 coenzymes of this vit.

Constituent of cytochrome C

reductase

Warburg-yellow enzyme

Fumarate dehydrogenase

Cheilosis

Glossitis

Seborrheic dermatitis

3. Vit. B (Niacin)

NAD and NADP are it’s

active forms which

operate as hydrogen and

electron transfer agents

They are co-enzymes for various types of dehydrogenases like

Alcohol dehydrogenase

Lactate dehydrogenase

Malate dehydrogenase

Pyruvate dehydrogenase

Pellagra C/B 3 D’s

Diarrhea

Dermatitis

Dementia

4. Vit. B (Pyridoxine)

Co-transaminase

Co-decarboxylase

Deaminase

Involved in synthesis of Co-A

Co enzyme for Kynureninase

[ vit- B6 deficiency Kynurenine levels , which is converted to xanthurenic acid which is a reliable criteria for B6 deficiency]

Epileptiform convulsion in infants

Sideroblastic anemia [ Vit — B6 is used in t/t of oxalate stone of kidney and homocystinuria]

5. Pantothenic acid

Active form is Co-A

Formation of Acetyl CoA

Formation of succinyl CoA

Oxidation of Fatty acids

Synthesis of Fatty acids

Carboxylase enzyme

G.I. symptoms

Changed sleep patterns

Easy fatigue

Burning foot syndrome

6. Biotin

Carboxylase enzyme

Leiner’s disease

Exfoliative dermatitis

7. Vit. B (cyanocobalamine

To convert — Methyl malonyl CoA succinyl CoA

Homocysteine to methionine

Ribonucleotide

Deoxyribonucleotide

Methyl malonylurea

Homocystinuria

Pernicious anemia

SCID

Vitamins, Harmones and Hemoglobin Flashcard List

82 flashcards
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
13)
14)
15)
16)
17)
18)
19)
20)
21)
22)
23)
24)
25)
26)
27)
28)
29)
30)
31)
32)
33)
34)
35)
36)
37)
38)
39)
40)
41)
42)
43)
44)
45)
46)
47)
48)
49)
50)
51)
52)
53)
54)
55)
56)
57)
58)
59)
60)
61)
62)
63)
64)
65)
66)
67)
68)
69)
70)
71)
72)
73)
74)
75)
76)
77)
78)
79)
80)
81)
82)