Vitamins, Harmones and Hemoglobin
The "c" terminal peptide of androgen binding protein is essential for? (AIPG 2007)
|A||Binding to promoter|
|B||Binding to gene|
|C||Binding to hormone binding domain|
Androgen acts by a nuclear mechanism similar to that employed by adrenal steroid
Binding of the receptor-steroid complex to chromatin may involve a prior activation step
Carboxy terminal of steroid receptor contains the DNA and hormone - binding domains and a second transactivation domain commonly referred to as AF-2. AF2 is a ligand dependant transactivator.
Hormone binding domain is closer to carboxy terminal.