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Biochemistry

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Vitamins, Harmones and Hemoglobin

Question
20 out of 30
 

The "c" terminal peptide of androgen binding protein is essential for? (AIPG 2007)



A Binding to promoter

B Binding to gene

C Binding to hormone binding domain

D Transcription efficacy

Ans. C Binding to hormone binding domain

Androgen acts by a nuclear mechanism similar to that employed by adrenal steroid

Binding of the receptor-steroid complex to chromatin may involve a prior activation step

Carboxy terminal of steroid receptor contains the DNA and hormone - binding domains and a second transactivation domain commonly referred to as AF-2. AF2 is a ligand dependant transactivator.

Hormone binding domain is closer to carboxy terminal.

Vitamins, Harmones and Hemoglobin Flashcard List

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