The commonest site for distant metastases in a patient of cancer of the breast is:
a. Most common site of distance metastatic is bone (Lumbar vertebrA.
b. Soft tissue, bony, and visceral (lung and liver) metastases each account for approximately one-third of sites of initial relapses.
c. The most common site of distant mets is lung followed by liver and then by bones.
d. However, by the time of death, most patients will have bony involvement.
e. Recurrences can appear at any time after primary therapy. Half of all initial cancer recurrences occur >5 years after initial therapy.
f. The choice of therapy requires consideration of local therapy needs, the overall medical condition of the patient, and the hormone receptor status of the tumor, as well as clinical judgment.
h. Other systemic treatments, such as strontium 89 and/or bisphosphonates, may provide a palliative benefit without inducing objective responses.