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Biochemistry

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Carbohydrates

Question
9 out of 40
 

The conversion of pyruvate to acetyl CoA and CO2:



A is reversible.

B involves the participation of lipoic acid.

C is activated when pyruvate dehydrogenase (PDH) complex is phosphorylated by PDH kinase in the presence of ATP.

D occurs in the cytosol.

Ans. B involves the participation of lipoic acid.

a. Lipoic acid is an intermediate acceptor of the acetyl group formed in the reaction. Pyruvate dehydrogenase complex catalyzes an irreversible reaction that is inhibited when the enzyme is phosphorylated.

b. The enzyme is located in the mitochondrial matrix. Biotin is utilized by carboxylases

Carbohydrates Flashcard List

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