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Physiology

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Central Nervous System

Question
18 out of 23
 

The inhibitory neurotransmitter in central nervous system is:



A Glutamate
B Aspartate

C Gamma-aminobutyric acid
D Taurine

Ans. C Gamma-aminobutyric acid
  1. The first neurotransmitter to be shown to produce presynaptic inhibition was gamma-aminobutyric acid (GABA). It acts via GABAA receptors; GABA increases chloride conductance Q.
  2. GABAB receptors are also present in the spinal cord and appear to mediate presynaptic inhibition via a G-protein that produces an increase in potassium ion conductance.
  3. Baclofen, is a GABAB agonist Q and is effective in treatment of spasticity of spinal cord injury and multiple sclerosis. Q

Central Nervous System Flashcard List

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