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Reproductive Physiology, Endocrinology, and Infertility

Question
15 out of 56
 

The most common cause of primary amenorrhea is: (AIIMS NOV 2012)



A Genital tuberculosis
B Ovarian dysgenesis

C Mullerian duct anomalies
D Hypothyroidism

Ans. B

Ovarian dysgenesis

1. Primary ovarian failure is associated with elevated plasma gonadotropin levels and can result from several causes.

2. The most frequent cause is gonadal dysgenesis, in which the germ cells are absent and the ovary is replaced by a fibrous streak.

3. Gonadal dysgenesis is the most common cause of primary amenorrhea, accounting for a third of such patients.

4. Mullerian agenesis (the Mayer-Rokitansky-Küster-Hauser syndrome) is second in frequency only to gonadal dysgenesis as a cause of primary amenorrhea.

Reproductive Physiology, Endocrinology, and Infertility Flashcard List

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