The most common site of heterotopic pancreatic tissue
a. Pancreatic tissue has been documented in ectopic sites in the gastrointestinal tract and even elsewhere.
b. The most common site for nodules of aberrant pancreatic tissue is on the wall of the stomach, duodenum or jejunum.
c. The nodules may be found in submucosa (75%) and in the muscular layer or subserous coat in the remainder.
d. The overall incidence and relative frequency with which it cause symptoms varies.
e. Autopsy studies have found heterotopic pancreatic tissue in the duodenum in as high as 14% of individuals.
f. Scattered pancreatic tissue has been found in Meckel's diverticulum, gallbladder, colon, Spleen, Liver, Bile ducts, mesentery or even omentum.
g. Enterogenous cysts of the thorax have been reported to contain typical pancreatic tissue, including islets.
h. With the advent of widespread upper gastrointestinal endoscopy and improvements in contrast studies of the alimentary tract, ectopic pancreas of the stomach and duodenum is being more frequently recognized.
i. The pathognomic radiological finding is a smooth, rounded or negative shadow with evidence of a tiny umbilication or even a small duct which may be outlined by a line of barium.
j. Probably most individuals with ectopic pancreas have no symptoms whatsoever.
k. However, abdominal pain suggestive of peptic ulcer disease sometimes occurs.