The most non-invasive technique for obtaining biopsy specimen from a mass in the body of pancreas is:
|C||Laparotomy and surgical excision of mass|
|D||Ultrasound guided percutaneous biopsy|
a. Biopsy to confirm the presence and identify the type of cancer is usually required before chemoradiation therapy of unresectable pancreatic tumors or neoadjuvant treatment of resectable tumors.
b. Percutaneous biopsy, performed with either CT or ultrasound guidance, or transduodenal biopsy, performed with endoscopic ultrasound guidance, is routinely employed in these situations.
c. Considerable controversy, however, surrounds the question of whether all patients with potentially resectable tumors should undergo preoperative biopsy.
d. Biopsy might yield false-negative results, and at least theoretically, transcutaneous biopsy could promote intraperitoneal dissemination of the tumor.
e. Performing the biopsy through a transduodenal approach would eliminate the concern of tumor dissemination