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Biochemistry

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Carbohydrates

Question
11 out of 40
 

The reaction catalyzed by phosphofructokinase:



A is activated by high concentrations of ATP and citrate.

B uses fructose 1-phosphate as substrate.

C is the rate-limiting reaction of the glycolytic pathway.

D is near equilibrium in most tissues.

Ans. C is the rate-limiting reaction of the glycolytic pathway.

a. Decreased lactate production in the erythrocyte indicates a defect in glycolysis.

b. Among patients exhibiting genetic defects of glycolytic enzymes, about 95 percent show a deficiency in pyruvate kinase, and four percent exhibit phosphoglucoseisomerase deficiency.

c. Pyruvate kinase deficiency is the second most common cause (after glucose 6-phosphate dehydrogenase deficiency) of enzyme deficiency–related hemolytic anemia.

Carbohydrates Flashcard List

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