56 out of 91
The results shown in the graph below were obtained in a comparison of positive inotropic agents. Which of the following statements is MOST correct? (LQ)
|A||Drug A is most effective|
|B||Drug B is least potent|
|C||Drug C is most potent|
|D||Drug B is more potent than drug C and more effective than drug A|
|E||Drug A is more potent than drug B and more effective than drug C|
Ans. A Drug A is most effective
- Graded dose-response curves must be used to determine maximum efficacy (maximal response).
- Quantal dose-response curves show only the frequency of occurrence of a specified response, which may be therapeutic (ED. or toxic (TD.. Dividing the TDs0 by the EDs0 gives the therapeutic index.