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Physiology

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Kidney

Question
2 out of 19
 

The status of fluid in distal convoluted tubule is always (AIPG 2009)



A Always hypotonic
B Hypertonic

C Isotonic
D Always hypertonic

Ans. A Always hypotonic

I. The descending limb of the loop of Henle is permeable to water, but the ascending limb is impermeable.

II. Sodium, potassium and chloride are co-transported out of the thick segment of the ascending limb.

III. Therefore, the fluid in the descending limb of the loop of Henle becomes hypertonic as water moves into the hypertonic interstitium.

IV. In the ascending limb, it becomes more dilute, and when it reaches the top, it is hypotonic to plasma because of the movement of sodium and chloride out to the tubular lumen.

V. Therefore, the fluid that is delivered to the distal convoluted tubule is always hypotonic.

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