The triad of Wernicke’s encephalopathy all except?
Thiamine (Vit B1) deficiency
Causes: Wernicke’s encephalopathy
1). Triad of Global confusion, Ophthalmoplegia, Ataxia (G.O.A.)
2). Prolonged untreated thiamine deficiency causes irreversible dementia / amnestic syndrome (Korsakoff’s psychosis)
3). In Korsakoff’s syndrome, the patient is unable to recall new information despite normal attention span, and level of consciousness.
4). Memory for new events is seriously impaired whereas memory of knowledge prior to the illness is relatively intact.
5). There is damage to the medial thalamic nuclei and mammillary bodies.
Korsakoff psychosis –amnesia & confabulation
Thiamine deficiency causes lactic acidosis (AIIMS Nov 10)