Toxic megacolon is due to
|D||Familial polyposis coli|
a. Toxic megacolon is a serious, life-threatening condition that can occur in patients with ulcerative colitis, Crohn's colitis, and infectious colitides such as pseudomembranous colitis.
b. This decompensation results in a necrotic, thin-walled bowel in which pneumatosis can often be seen radiographically.
c. Total proctocolectomy in the urgent setting carries a prohibitively high mortality rate, and the leak rate from a primary anastomosis is unacceptably high.
d. A total abdominal colectomy with ileostomy and preservation of the rectum is therefore the preferred operation for this condition.