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ARSENIC POISONING used in Abortion stick,

  1. Aphrodisiac,  found in Ashes n charred bones
  2. Aldrich Mee’s lines ( leuchoparonychia ) on nails
  3. Rain drop pigmentation of skin
  4. Red velvety appearance of stomach mucosa Subendocardial hg. Of heart
  5. calcium sodium Edetate is antidote
    1. Neuropathy (motor & sensory), optic Neuritis
    2. Iron dialysed or fresh hydrated ferric oxide
    3. Cholera** (Rice water stool)
  6. White arsenic -  Arsenious oxide (Sankhya)
  7. Arsenious trioxide resembles Addison’s disease
  8. BAL is antidote ( c/I in café  Cadmium & Ferrum poisoning )
  9. Marsh test, Reinsh test
  10. Measles like rashes
  11. Alkali is contraindicated
  12. Retards decomposition (Carbolic acid, Organophosphorus, Strychnine( Nux Vomica, Endrin, Dhatura, Arsenic, Zinc Chloride)
  13. Rigor mortis lasts longer than usual*
  14. paris green (Copper acetoarsenate)
  15. Hyperkeratosis & Hyper pigmentation of palm & soles
  16. deposited in Hair after 1 week
  17. Liver :- Cirrhosis, Portal Hypertension
  18. Basal cell carcinoma
  19. Sub endocardial petechial haemorrhage of the heart.

Mercury Poisoning

  1. Vaporized mercury if inhaled is poisonous (glass industry worker)
  2. Rubbing on the skin is poisonous ( finger print powder contains mercury).     
  3. Metallic mercury when swallowed is not poisonous .
  4. Pharoah’ serpent ( sulphocyanide of mercury stick) swallowed accidentally
  5. Mercurialentis (brownish deposit of mercury on ant lens capsule known as
  6. “Brown malt reflex” *) bilateral , no effect on visual acuity.
  7. Minamata disease,
  8. Mandible necrosis,
  9. Membranous colitis,
  10. Metallic taste,
  11. Membranous glomerulonephritis
  12. Fatal dose – 5 gm ( 1 – 4 gm )
  13. Fatal period – 5 days ( 3 – 5 days)
  14. Erythrism ** (shy, timid, mental depression, loss of memory )
    1. Acrodynia *( Pink disease )
    2. Proximal renal tubular necrosis *
    3. Danbury shakes, Hatter’s shakes (AIIMS Nov 09), Glass blower’s shakes, Concussio mercuralis
    4. Mercuric chloride (corrosive sublimate) is most toxic form
    5. Quick silver, sodium formaldehyde sulphoxylate
    6. Hydragyrasim ( chronic poisoning )
    7. British antilewisite, penicillamine

Lead Poisoning

  1. Anemia, Abortion, Anorexia
    1. Basophilic stippling*
    2. Burtonion line (blue colored line in upper jaw due to lead sulphide)*
    3. (BLUISH LINE on the gums seen in Bismuth, lead, cUpper, Iron, Silver & Hg poisoning)
    4. Bones : have increased radio-opaque band of lines at metaphysis*
  2. Colic, Constipation
    1. Dry belly ache*
    2. Drop : wrist* (radial nerve), foot (deep peroneal nerve)
    3. Dyspepsia
    4. Dysmenorrhoea*
  3. Encephalopathy (more common in children)*
  4. SSterility in both males and females*
    1. Plumbism
    2. Pallor (facial, most consistent and the earliest symptom)*
    3. Porphyrins in urine ( >500mcg/day)* , corpoporphyrins give red fluoroscence in uv light.
fatal period – 1-2 days
conc. of lead in blood – 0.1 - 0.2 (0.1 – 0.6mg/100ml)
chronic poisoning – 1-2 mg daily
fatal dose - 20 mg
occurs mostly from – lead Acetate
chelating agent – BAL
most effective antidote – Calcium Disodium Edetate
  1. COPPER (TAMBA) , ZINC
     
    P - Ptylasim
     
    P - Potassium Ferro cyanide
     
    P - Penicillamine
     
    G - Golden colour hairs
  2. Zinc
     
    Exposure to zinc oxide fumes by breathing it from welding or heating glavanized metal. Toxicity resembles malarial chills,  Muscle aches, Gastroenteritis features Complete recovery in 24- 48 hrs. Also known as smelter’s fever,Metal fume fever ( also caused by copper , magnesium, nickel , mercury)




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