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Biochemistry

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Lipid

Question
57 out of 63
 

Transition temperature of lipid bilayers of cell membranes is increased by



A Cholesterol

B Saturated fatty acids

C Unsaturated fatty acids

D Hydrocarbons

Ans. B saturated fatty acid

a. The fluid mosaic model of membrane structure proposed by Singer and Nicholson, is now widely

accepted.

b. Transition temp. Tm The temperature at which the structure undergoes from ordered stiff to

disordered fluid, i.e. melt

a. The Longer and more saturated fatty acid chains interacts more strongly with each other via their

Longer Hydrocarbon chains thus Tm, stiff i.e. higher temperature is required to increase the fluidity of the bilayer.

b. Unsaturated fatty acids: cis configuration →↑fluidity of lipid bilayer i.eTm

c. Cholesterol:-

d. At temp. below Tm →↑ fluidity

e. At temp. above Tm →↑ limiting the fluidity

f. At high cholesterol: phospholipid ratio Transition temperature TM are abolished altogether.

Lipid Flashcard List

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