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Paediatric

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CVS

Question
63 out of 63
 

Treatment of choice for Kawasaki disease: (AIIMS Nov 2011)



A IV immunoglobulin
B Steroid

C Azathioprine
D Cyclosporine

Ans. C

Lymph node biopsy is diagnostic

Kawasaki disease

1. Kawasaki disease is the most common form of vasculitis that primarily affects children.

2. The disease produces irritation and inflammation of many tissues of the body, including the hands, feet, whites of the eyes, mouth, lips, and throat. High fever and swelling of the lymph nodes in the neck also are characteristic of this illness. The inflammation is uncomfortable, but resolves with time.

3. However, the main threat from Kawasaki disease comes from its effect on the heart and blood vessels. Heart-related complications can be temporary or may affect the child long-term. The heart, particularly the coronary arteries, is affected in as many as 25% of children with Kawasaki disease.

4. Another name for Kawasaki disease is mucocutaneous lymph node syndrome.

5. No laboratory test can diagnose Kawasaki disease with 100% certainty.

6. Treatment for Kawasaki disease is most effective if given in the first 10 days of the illness.

7. There are two principal treatments:

a. Intravenous gamma globulin (IVIG) is used to shorten the acute phase of Kawasaki disease and prevent coronary damage

b. Aspirin is used to decrease inflammation and lower fever, as well as prevent blood clots.

CVS Flashcard List

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