True about Binswanger’ disease is?
|A||White matter involved|
|B||Amyloid angiopathy occurs|
|D||All of the above|
All of the above
Vascular Dementia (Ref. Hari-18th ed., pg – 3309)
Dementia associated with cerebral vascular disease can be divided into two general categories:
1). Multi-infarct dementia
2). Diffuse white matter disease (also called leukoaraiosis, subcortical arteriosclerotic encephalopathy or Binswanger's disease).
3). With normal aging, there is also an accumulation of amyloid in cerebral blood vessels, leading to a condition called cerebral amyloid angiopathy of aging (not associated with dementia), which predisposes older persons to hemorrhagic lobar stroke.
4). AD patients with amyloid angiopathy may be at increased risk for cerebral infarction.