True about Lichen planus - (AIPG 2011)
|A||Basal cell degeneration|
|B||Colloid bodies seen|
|C||Epidermal hyperplasia in chronic cases|
|D||Wickham's striae seen|
i.e., Basal cell degeneration; B . i.e., Colloid bodies seen; C . i.e., Epidermal hyperplasia in chronic cases; D . i.e., Wickham's striae seen & E . i.e., Autoimmune disease
a. Basic pathology in Lichen planus is basal cell degeneration.
b. Colloid bodies (Civatte bodies or cytoid bodies) are seen in macrophages.
c. There is epidermal thickening especially of granular layer.
d. Wickam's stria are characteristic of Lichen planus.
e. Lichen planus is considered to be an autoimmune disorder as histopathology suggests an immunological response to an antigen present in basal cell layer of epidermis.