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Medicine

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Endocrine

Question
10 out of 15
 

True about Somogyi phenomena 3am 8 am



A Hypoglycemia Hypoglycemia

B Hypoglycemia Hyperglycemia

C Hyperglycemia Hyperglycemia

D Hyperglycemia Hypoglycemia

Ans. B

Hypoglycemia

1). Somogyi phenomena

a. It is the morning (8 am) hyperglycemia which follows hypoglycemia at late night (2am).

b. Hypoglycemia occurs due to overdose of insulin at night leading to release of counter regulatory hormones (glucagon, 1st to be released, followed by adrenaline, steroids, growth hormone, and thyroxine).

c. Treatment is to reduce the night dose of insulin.

2). Dawn phenomena

a. It is morning (8 am) hyperglycemia which follows hyperglycemia at late night (2am).

b. This is due to nocturnal increase release of growth hormone.

c. Treatment: is to increase the night dose of insulin.

Pseudo hypoglycemia

Extra edge: Hypoglycemia can be artifactual; hyperleukocytosis from leukemia, myeloproliferative diseases, leukemoid reactions, or colony-stimulating factor treatment can increase glucose consumption in the test tube after blood is drawn, leading to pseudo hypoglycemia. (Ref. Hari 18th ed. Pg- 2274)

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