True about genomic imprinting - (PGI Nov 10)
|A||Different expression of gene depending on parent of origin|
|B||Prader- Willi syndrome is maternal deletion of chromosome 15|
|C||Angelman syndrome is due to paternal deletion of chromosome 15|
|D||Uniparental disomy is other name of genomic imprinting|
a. The expression of disease depending on whether the functional gene is inherited from the male or female parent (one parent only) is termed as genomic imprinting.
The phenomenon referred to as genomic imprinting leads to preferential expression of an allele depending on its parental origin.