True about infant leukemia is (AIIMS Nov 2014)
|A||It occur below 1 year|
|B||There is a rearrangement of MLL gene – on chromosome 11|
|C||Leukemia cutis is there|
|D||All of the above|
All of the above
1. It occurs before 1 yr.
2. In 2/3 of cases, there is a rearrangement of MLL gene – on chromosome 11.
3. It has poor prognosis and very high relapse rate.
4. Leukemia cutis (subcutaneous nodules) and tachypnea due to diffuse pulmonary infiltration by leukemia cell is common finding in infants.