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Pharmacology

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Respiratory Systems

Question
44 out of 47
 

True about zafirlukast is (DNB Dec, 2012)



A It inhibit lipooxygenase pathway

B It decreases the frequency of asthma attacks as com- pared to glucocorticoids

C It blocks LT receptor

D It is effective in acute bronchial asthma

E It can be administered orally

Ans. A It inhibit Lipoxygenase pathway; C. It blocks L T receptor; (e) Given orally (Ref. : KDT 6th/222-223)

Zafirlukast and montelukast are cysteinylleukotriene receptor antagonists. They cause modest improvementinha function and reduction in asthma symptoms and lessen the need for beta-agonist rescue herapy. These drugscan~ considered as alternatives to low-dose inhaled corticosteroids in patients with persistent asthma.

Zafirlukast is long acting and can be given twice to once daily orally. It is a modest bronchodilator that reduC!!

asthma morbidity, provides protection against exercise induced asthma and diminishes nocturnal symptoms.

These are less effective than corticosteroids.

Respiratory Systems Flashcard List

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