True regarding MOTS (Mycobacteria other than tuberculosis)? (AIIMS May 2010)
|A||Always caused disseminated infection|
|B||Person to person transmission only|
|C||Immunocompetent persons can also be infected|
|D||MOTS infection interferes protection given by BCG results.|
MOTS infection interferes protection given by BCG results.
1). The designation nontuberculous mycobacteria (NTM) encompasses the mycobacterial species other than organisms of the Mycobacterium tuberculosis complex and M. leprae.
2). Disseminated M. kansasii disease occurs principally among patients with advanced AIDS and CD4 T cell counts of 100/µL. It has also seen in patients with leukemia, lymphoma, or solid-organ transplantation.
3). Asymptomatic infections with NTM are common in humans and are acquired most often from childhood contact with soil, water.
4). Though occasionally they may cause disease in immunocompetent, if i have to choose one correct, i would go with the option d. They affect the protective response to BCG.