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Biochemistry

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Vitamins, Harmones and Hemoglobin

Question
11 out of 30
 

True regarding conversion of deoxyhemoglobin to oxyhemoglobin is:



A Binding of O2 causes release of H+

B One mole of deoxyhemoglobin binds two moles of 2,3 DPG.

C pH of blood has no affect on the binding of O2

D Binding of O2 causes increased binding of 2,3 DPG.

Ans. A Binding of O2 causes release of H+

Binding of O2 to deoxyhemoglobin in lungs causes release of proton (H+). This is responsible for Bohr effect.

One mole of deoxyhemoglobin binds one mole of 2,3 DPG.

2,3- DPG binds to deoxygenated (T) form of Hb & binding of O2 to Hb decreases the binding of 2,3-DPG.

2,3-DPG decreases the affinity of Hb molecule for O2 thus increase in DPG conc, shifts O2- Hb dissociation curve to right.

Vitamins, Harmones and Hemoglobin Flashcard List

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