Oncology and Fibroids
Tumor marker CA 125 is for: (LQ)
a. Evaluation of patients with suspected ovarian cancer must include measurement of serum levels of the tumor marker CA-125. CA-125 are glycoproteins with molecular masses between 220-1000 kDa. Between 80 and 85 % of patients with epithelial ovarian cancer have levels of CA-125 ≥ 35 U/mL.
b. Other malignant tumors can also raise CA-125 levels, including cancers of the endometrium, cervix, fallopian tubes, pancreas, breast, lung, and colon. Certain nonmalignant conditions that can raise CA-125 levels include pregnancy, endometriosis, pelvic inflammatory disease, and uterine fibroids. One percent of normal females have serum CA-125 levels >35 U/mL.
c. However, in postmenopausal women with an asymptomatic pelvic mass and CA-125 levels ≥ 65 U/mL; the test has a specificity of 78 %.