Gram Positive Bacilli
Two of three family members had dinner at a local restaurant and within 48 hours, experienced double vision difficulty in swallowing and speaking and breathing problems. These symptoms are consistent with which of the following? (AIPG 2009)
|A||Activation of cyclic AMP|
|C||Ingestion of a neurotoxin|
|D||Invasion of the gut epithelium by an organism|
a. Botulinum growing in food produces a potent neurotoxin that causes diplopia, dysphagia, respiratory paralysis, and speech difficulties when ingested by humans.
b. The toxin is thought to act by blocking the action of acetylcholine at neuromuscular junctions. Botulism is associated with high mortality; fortunately, C. botulinum infection in humans is rare.