Pchycoactive Substance Use Disprder
Two policeman pullover the driver of a car a 20-year old man, for speeding. They immediately notice a strong smell of alcohol on his breath and administer a Breathalyzer test. According to the instrument, the man’s blood alcohol level is 200mg/dl, but he does not show any typical signs of intoxication. His gait is stedy, his speech is clear. What is the most likely explanation for such presensation ? (AIIMS Nov 2009)
|A||The Breathalyzer is defective.|
|B||A value of 200mg/Dl is below the intoxication level|
|C||The man has developed a tolerance to the effect of alcohol|
|D||The man has alocohol dependence|
a. After prolonged use, most drugs of abuse (and some medications) produce adaptive changes in the brain that are manifested by a markedly diminished responsiveness to the effects of the substance that has been administered over time, a phenomenon called tolerance.
b. Anyone who does not show signs of intoxication with an alcohol level of 150 mg/dL has developed a considerable tolerance.