13 out of 32
Tzanck smear in a patient of bullous lesions shows: (LQ)
|A||Absence of melanin pigment|
The diagnosis of pemphigus can be made by a skin biopsy and demonstration of acantholytic cells in the Tzanck smear from the lesions. Acantholysis is the loss of cohesion between epidermal or adnexal keratinocytes.