Female Genital Tract
Uterine leiomyoma is least likely to undergo: (LQ)
|A||Malignant change :|
Secondary changes (degenerations) in
• Atrophy: It can be:
− After menopause
− After delivery
Tumour becomes firmer and more fibrotic. It is due to diminished blood supply.
• Calcareous degeneration: Phosphates and carbonates of lime are deposited in the periphery along the course of the vessels.
− womb-stones' in graveyard: In old patients with long-standing myomas.
• Red (Carneous) degeneration: It is more common during. pregnancy. The myoma becomes tense and tender and causes severe abdominal pain with constitutional upset and fever. The tumour itself assumes a peculiar purple-red color and develops a fishy odour.
− Although the patient is febrile with moderate leucocytosis and raised ESR, the condition is an aseptic one.
− It needs to be differentiated from-
− Twisted ovarian cyst
− Accidental hemorrhage
• Sarcomatous change: It is extremely rare. Incidence is no more than 0.5% of all myomas.
− Intramural and submucous tumors have a higher potential than sub-serous.
− It is rare for malignant change to develop in i women under the age of 40'
− It is highly malignant and spreads through blood'
• Other complications:
− Capsular hemorrhage
− Associated endometrial carcinoma