Vasanti, a 25-year-old-girl, presents with complaints of fever and weakness. On examination there is splenomegaly of 3 cm below the costal margin. Hb is 8 gm/dL, TLC is 3,000/mm3, platelet count is 80,000/mm3.
Which of the following is the least likely diagnosis: (AIIMS Nov 2010)
|A||Acute lymphocytic leukemia|
|B||Anemia of chronic disease|
Criteria for Severe Aplastic Anemia: (Any two blood criteria and either one-marrow criterion).
a. Neutrophils < 500/μl
b. Platelets < 20,000/μl
c. Reticulocytes < 1%
2. Bone marrow
a. Severe hypocellularity
b. Moderate hypocellularity with < 30% of residual cells being hematopoietic